CRISPR optimization built for decisions, not dashboards.
GeneForge is Bajpai Labs' CRISPR and genomic optimization platform: genome-wide guide screening that ranks your best sequences before any expensive synthesis or wet-lab validation begins.
Get gene editing teams to the right sequences faster.
GeneForge exists because most CRISPR programs waste time and capital on manually designed guides that fail off-target safety review or first-pass validation. We replace slow CRO workflows with genome-wide screening and ranked, manufacturing-ready deliverables.
Surface the 10 to 20 guide sequences worth validating, not a handful of hand-picked designs. Every pipeline run is scoped to a gene editing decision your team actually needs to make.
From target locus upload through off-target screening, tissue chromatin weighting, and manufacturability scoring: one integrated pipeline with a ranked deliverable.
Typical engagements deliver in 10 to 14 days with full technical documentation. Built for programs that cannot wait 8 to 10 weeks for CRO guide design.
Every engagement returns ranked sequences with tiered off-target risk classification and the validation playbook your scientists need before manufacturing commitment.
Bridge research and clinical gene editing.
“Enable gene therapy teams to edit with confidence, by synthesizing only the guide sequences and constructs that computational genomics says are safe and effective.”
The principles behind every guide design run.
- Safety before efficiency
Off-target risk classification comes before on-target ranking. A highly efficient guide at a pathogenic off-target site is worse than no guide at all.
- Production accountability
Ranked output with full technical documentation. Not benchmark leaderboard claims.
- Research-driven methods
Published, peer-reviewed techniques composed with proprietary scoring calibrated on wet-lab validation outcomes.
- Senior-led engagement
Direct access to the architects who designed the pipeline, from scoping through delivery.
A product from a research-driven AI lab.
GeneForge is one of Bajpai Labs' specialized platforms, alongside HelixForge for drug discovery and other flagship products in enterprise AI and hybrid computing. The same research depth and production accountability that drives the parent lab drives every GeneForge engagement.